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It showed potential benefits for CKD patients, particularly those who are overweight or obese

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Definitive answers are eagerly awaited from ongoing trials like the FOCUS study (NCT03811561), which is specifically designed to clarify the long-term impact of semaglutide on diabetic eye disease [96]

Peroxisomes contain also CRAT, a membrane carnitine octanoyltransferase (CROT) inhibited by malonyl-CoA, and another soluble carnitine acyltransferase not inhibited by malonyl-CoA[4]

ROS also impair proteasome and mitochondrial function